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Rho A (R182) Peptide

Cat no: BS1782P

Rho A (R182) Peptide

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1 (A and B), Rap 2, R-Ras and Ral (A and B), exhibit approximately 50% amino acid homology to Ras. The three mammalian Rho proteins (A, B and C) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function

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SPECIFICATIONS

Catalog Number

BS1782P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Rho A (R182). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P61586

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1782 Rho A (R182) pAb.

Alternative Names

RHOA; ARH12; ARHA; H12; RHO12; RHOH12

SUPPLIER INFO

Bioworld Technology, Inc.

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