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Rho D Peptide

Rho D Peptide

Cat no: BS5898P

Supplier: Bioworld Technology, Inc.
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Upon activation, the small GTPase Rho D (also designated RhoHP1 and ARHD) contributes to rearrangement of the actin cytoskeleton and cell surface and also governs endosome motility and distribution. The effects of Rho D antagonize those of its family member, Rho A, by dissasembling actin stress fibers normally enhanced by Rho A. Additionally, Rho D disengages focal adhesions, resulting in retardation of cell migration. Accordingly, transfection of a constitutively active form of Rho D (designated Rho D G26V) reverses the invasive phenotype of Galphaolf induced cells, implying the possiblity of a therapeutic use for activated Rho D in counteracting tumor metastasis.
Catalogue number: BS5898P
Applications: Block/Neutralize/Inhibit
Swiss prot: O00212
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Rho D. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1; RHOD; ARHD
Additional info: This peptide can be used with studies using BS5898 Rho D pAb.

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