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ROR(gamma) pAb

ROR(gamma) pAb

Cat no: BS5915

Supplier: Bioworld Technology, Inc.
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The nuclear orphan receptors ROR(alpha) and ROR(gamma) are members of the nuclear hormone receptor superfamily. This family acts by directly associating with DNA sequences known as hormone response elements (HREs) and typically binds DNA as either homo- or heterodimers. ROR(alpha) and ROR(gamma) are unique in that they bind DNA as monomers. ROR(alpha) has multiple isoforms that share common DNA- and putative ligand-binding domains, but differ in their aminoterminal domains, which are generated by alternative RNA processing. ROR(gamma) comprises a 560 amino acid protein that shares 50% amino acid identity with ROR(alpha) and is most highly expressed in skeletal muscle. Although these proteins are considered
Catalogue number: BS5915
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P51449
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 114-159 of Human ROR(gamma).
Species: ROR(gamma) pAb detects endogenous levels of ROR(gamma) protein.
Molecular weight: ~ 63 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Nuclear receptor ROR-gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; Retinoid-related orphan receptor-gamma; RORC; NR1F3; RORG; RZRG
Additional info: For research use only, not for use in diagnostic procedure.

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