RUNX-2 (N278) pAb

Cat no: BS2831

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5'- PYGPYGGT-3' in a number of promoters and enhancers. They include LCK, T-cell receptor enhancers, and various bone related genes such as osteocalcin, osteopontin, and bone sialoprotein. As a result of this, RUNX2 is involved in osteoblastic differentiation and skeletal morphogenesis. RUNX2 contains a proline/serine/ threonine-rich region at its C-terminus that has shown to be critical for its transcriptional activity.

Catalogue number:	BS2831
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunofluorescence, Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q13950
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 246-297 of Human RUNX-2.
Species:	RUNX2 (N278) pAb detects endogenous levels of RUNX2 protein.
Molecular weight:	~ 57 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	CASP3; APOPAIN; CASP-3; CPP-32; CPP32; CPP32B; EC 3.4.22.-; SCA-1; YAMA;
Additional info:	For research use only, not for use in diagnostic procedure.

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RUNX-2 (N278) pAb

Cat no: BS2831

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