RUNX3 (D196) Peptide

RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX3 is expressed in cells of hematopoietic origin, including myeloid and B-cell lines and spleen. By playing a role in controlling the growth and differentiation of gastric epithelial cells, RUNX3 is a strong candidate as a gastric cancer tumor suppressor. Specifically, hypermethylation inactivates the gene encoding RUNX3. The detection of hypermethylation at multiple regions within the RUNX3 CpG island may aid in the diagnosis and risk assessment of gastric cancer.

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SPECIFICATIONS

Catalog Number

BS9227P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide RUNX3 (D196). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q13761

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9227 RUNX3 (D196) pAb.

Alternative Names

AML 2; AML2; CBF alpha 3; CBF-alpha-3; CBFA 3; CBFA3; CBFA3; Core binding factor alpha 3 subunit; core binding factor; Core binding factor runt domain alpha subunit 3; Core binding factor subunit alpha 3; core-binding factor; core-binding factor; Core-binding factor subunit alpha-3; FLJ34510; MGC16070; Oncogene AML 2; Oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; Pebp2a3; PEBP2aC; PEBP2aC; Polyomavirus enhancer binding protein 2 alpha C subuni