SAA1 pAb

The serum amyloid A (SAA) family of proteins is encoded by multiple genes, which display allelic variation and a high degree of homology in mammals. The four members of the SAA gene family are clustered on human chromosome 11p15.1. Three SAA genes are differentially expressed and encode small apolipoproteins. SAA1 and SAA2 encode the acute phase SAAs (A-SAAs), and SAA4 encodes the constitutively expressed SAA (C-SAA). A fourth locus, SAA3 is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor. Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.

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SPECIFICATIONS

Catalog Number

BS6727

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human SAA1.

Species

SAA1 pAb detects endogenous levels of SAA1 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P0DJI8

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 14 kDa

Alternative Names

Amyloid fibril protein AA; Amyloid fibrils; Amyloid protein A; Fibrils; MGC111216; OC; PIG 4; PIG4; SAA 1; SAA 2; SAA; SAA; SAA1; SAA2; Serum amyloid A protein precursor; Serum amyloid A1 isoform 1; Serum amyloid A1 isoform 2; Serum amyloid protein A(4-101); TP53I4; Tumor protein p53 inducible protein 4;