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SAE1 (L247) Peptide

SAE1 (L247) Peptide

Cat no: BS1457P


Supplier: Bioworld Technology, Inc.
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Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1.
Catalogue number: BS1457P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9UBE0
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide SAE1 (L247). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SAE1; AOS1; SUA1; UBLE1A
Additional info: This peptide can be used with studies using BS1457 SAE1 (L247) pAb.

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