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SAE1 (L247) Peptide

Cat no: BS1457P

SAE1 (L247) Peptide

Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1.

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SPECIFICATIONS

Catalog Number

BS1457P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide SAE1 (L247). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9UBE0

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1457 SAE1 (L247) pAb.

Alternative Names

SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SAE1; AOS1; SUA1; UBLE1A

SUPPLIER INFO

Bioworld Technology, Inc.

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