Sam 68 (Y145) Peptide

SAM68 is recruited and tyrosine phosphorylated by several receptor systems, and once it is phosphorylated, it functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins.It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. It also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

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SPECIFICATIONS

Catalog Number

BS2952P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Sam 68 (Y145). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q07666

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2952 Sam 68 (Y145) pAb.

Alternative Names

KH domain-containing; RNA-binding; signal transduction-associated protein 1; GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68; KHDRBS1; SAM68