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Sarcoglycan-(alpha) pAb

Sarcoglycan-(alpha) pAb

Cat no: BS5920

Supplier: Bioworld Technology, Inc.
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The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated (alpha)-, (beta)-, (gamma)- and (delta)-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, (beta)- and (delta)-sarcoglycans are associated with E-sarcoglycan, a glycoprotein homologous to (alpha)-sarcoglycan. Additionally, a complete deficiency in (delta)-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Catalogue number: BS5920
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ug/100ul
Swiss prot: Q16586
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200 IP: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 209-254 of Human Sarcoglycan-(alpha).
Species: Sarcoglycan-(alpha) pAb detects endogenous levels of Sarcoglycan-(alpha) protein.
Molecular weight: ~ 50 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-sarcoglycan; Sarcoglycan (alpha); (alpha)-Sarcoglycan; (alpha)-SG; SG-(alpha); SG(alpha); Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2; Dystroglycan 2; Dystroglycan2; SGCA; ADL; DAG2;
Additional info: For research use only, not for use in diagnostic procedure.

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