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Sarcoglycan-(beta) (V136) pAb

Sarcoglycan-(beta) (V136) pAb

Cat no: BS3518

Supplier: Bioworld Technology, Inc.
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Four sarcoglycan subunit proteins, designated (alpha)-, (beta)-, (gamma)- and (delta)-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, (beta)- and (delta)-sarcoglycans are associated with E-sarcoglycan, a glycoprotein homologous to (alpha)-sarcoglycan. Additionally, a complete deficiency in (delta)-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Catalogue number: BS3518
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q16585
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 102-158 of Human Sarcoglycan-(beta).
Species: Sarcoglycan-(beta) (V136) pAb detects endogenous levels of Sarcoglycan-(beta) protein.
Molecular weight: ~ 38 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: SGCB; 43DAG; A3B; BETA-SARCOGLYCAN; BETA-SG; LGMD2E; SGC
Additional info: For research use only, not for use in diagnostic procedure.

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