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SCAMP1 Peptide

Cat no: BS5921P

SCAMP1 Peptide

Secretory carrier membrane proteins (SCAMPs) are components of the post Golgi membranes and are invovled in endocytosis, vesicle recycling and membrane trafficking. The structural features of SCAMPs include multiple N-terminal NPF repeats and four highly conserved transmembrane regions. These NPF repeats frequently interact with EH domain proteins and aid in the budding of transport vesicles from the plasma membrane or the Golgi complex. Endocytic budding at the plasma membrane and vesicle budding at the trans-Golgi complex facilitates binding of SCAMP proteins to EH domain proteins. SCAMPs exist as distinct but related proteins that include SCAMP1, SCAMP2, and SCAMP3. Tyrosine-phosphorylation by the epidermal growth factor-receptor of SCAMP1 and SCAMP3 suggests that SCAMPs are regulated by phosphorylation. Although SCAMPs are ubiquitously expressed throughout all tissue, in neural tissue the synaptic vesicles express a particularly high concentration of SCAMP1.

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SPECIFICATIONS

Catalog Number

BS5921P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide SCAMP1. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O15126

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5921 SCAMP1 pAb.

Alternative Names

Secretory carrier-associated membrane protein 1; Secretory carrier membrane protein 1; SCAMP

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