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SCGB1A1 pAb

SCGB1A1 pAb

Cat no: BS6758

Supplier: Bioworld Technology, Inc.
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SCGB1A1 protein, a homologue of rabbit uteroglobin, is a phospholipase A2 inhibitor. SCGB1A1 is regulated by AP-1, octamer, and hepatocyte nuclear factor-3 (HNF-3) family transcription factors. SCGB1A1 expression changes in relation to the ovarian menstrual cycle, and expression in human endometrium may be stimulated by progesterone, suggesting that SCGB1A1 may regulate eicosanoid levels in the human uterus. SCGB1A1 is expressed in nonciliated airway epithelial cells in the lung and in urogenital secretions. SCGB1A1 is involved in modulating inflammation in airway passages and may play a role in asthma. Overexpression of SCGB1A1 in the non-small cell lung cancer cell line A549 was shown to result in the near absence of MMP-2 and MMP-9 matrix metalloproteinases and a reduction in invasiveness, indicating that loss of SCGB1A1 may contribute to carcinogenesis.
Catalogue number: BS6758
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P11684
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human SCGB1A1.
Species: SCGB1A1 pAb detects endogenous levels of SCGB1A1 protein.
Molecular weight: ~ 10 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Uteroglobin; Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1; SCGB1A1; CC10; CCSP; UGB
Additional info: For research use only, not for use in diagnostic procedure.

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