SCK Peptide

Cat no: BS5923P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events. Shc-like protein (Sck) is a neuronal adaptor protein that contains an N-terminal PTB (phosphotyrosine binding) domain, a collagen homology (CH) domain, and a conserved C-terminal SH2 domain. Human Sck transcripts are present at high levels in liver, pancreas, prostate and ovary. In vascular endothelial cells, Sck participates in VEGF-induced signal transduction. Treatment of human umbilical vein endothelial (HUVEC) cells with VEGF induces recruitment of Sck to tyrosine-1175 of the kinase insert domain-containing receptor (KDR) and enhances Sck tyrosine phosphorylation.

Catalogue number:	BS5923P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P98077
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide SCK. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	SHC-transforming protein 2; Protein Sck; SHC-transforming protein B; Src homology 2 domain-containing-transforming protein C2; SH2 domain protein C2; SHC2; SHCB
Additional info:	This peptide can be used with studies using BS5923 SCK pAb.

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SCK Peptide

Cat no: BS5923P

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