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Semaphorin 4F (PRO2353, SEMA4F, SEMAM, SEMAW) (APC)

Cat no: 145603

Semaphorin 4F (PRO2353, SEMA4F, SEMAM, SEMAW) (APC)

Semaphorin 4F (Sema4F; also known as Sema W) is a 90-100kD, class IV member of the semaphorin family of proteins. It is expressed by select cell types, including Schwann cells and neurons, and likely acts as an inhibitor of cell proliferation by Schwann cells, and a regulator of postsynaptic glutamatergic synapses on neuron dendrites. Mature mouse Sema4F is a type I transmembrane protein that is 737 amino acids (aa) in length. It contains a 627 aa extracellular region (aa41-667) that is characterized by the presence of one Sema domain (aa71-493), a PSI region (aa518-569), and a C2-type Ig-like domain (aa 586-641). Over aa41-667, mouse Sema4F shares 92% and 98% aa identity with human and rat Sema4F, respectively.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at 12 months at 4 degrees C. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyaninconjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

145603

Size

100Tests

Applications

FC

Hosts

Rat

Reactivities

Mouse

Form

Supplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).

P Type

Mab

Purity

Purified by Protein A or G affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes mouse Semaphorin 4F.

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