SEPT6 (Septin-6, KIAA0128, SEP2)

Cat no: S0950-15A

Supplier: United States Biological

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Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:4000 Western Blot: 0.03-1ug/ml, observed in human testis, Thyroid Gland and MOLT4 cell lysates on ~50kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S0950-15A
Reactivities:	Human, Bovine, Canine
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Kremer BE, Adang LA, Macara IG. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell. 2007 Sep 7;130(5):837-50.
Additional info:	Recognizes human SEPT6. Species sequence homology: Bovine and canine.

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SEPT6 (Septin-6, KIAA0128, SEP2)

Cat no: S0950-15A

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