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Septin 1 (D205) pAb

Septin 1 (D205) pAb

Cat no: BS2111

Supplier: Bioworld Technology, Inc.
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The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGF(beta) signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGF(beta) or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.
Catalogue number: BS2111
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q8WYJ6
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 169-224 of Human Septin 1.
Species: Septin 1 (D205) pAb detects endogenous levels of Septin 1 protein.
Molecular weight: ~40 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Peanut-like protein 2; Brain protein H5; Cell division control-related protein 2; hCDCREL-2; Bradeion beta; CE5B3 beta; Cerebral protein 7; 40060; ARTS. CE5B3. H5. PNUTL2. hCDCREL-2. hucep-7
Additional info: For research use only, not for use in diagnostic procedure.

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