Septin 1 (D205) Peptide

The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGFbeta signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGFbeta or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.

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SPECIFICATIONS

Catalog Number

BS2111P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Septin 1 (D205). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q8WYJ6

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2111 Septin 1 (D205) pAb.

Alternative Names

Peanut-like protein 2; Brain protein H5; Cell division control-related protein 2; hCDCREL-2; Bradeion beta; CE5B3 beta; Cerebral protein 7; 40060; ARTS. CE5B3. H5. PNUTL2. hCDCREL-2. hucep-7