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Serotonin Receptor 1A

Cat no: S1001-15C

Serotonin Receptor 1A

Serotonin Receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin Receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin Receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.\n\nApplications:\nSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.\n\nRecommended Dilutions: \nWestern Blot: 0.5ug/ml detects Serotonin Receptor 1A on 10ug of rat brain tissue lysate. Band is observed at ~40kD. Calculated MW is 46kD.\nImmunohistochemistry: 1:400 detects Serotonin Receptor 1A in normal human brain tissue.\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nRat brain tissue lysate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S1001-15C

Size

100ug

Applications

IHC, WB

Hosts

Mouse

Reactivities

Hum, Rat

Form

Supplied as a liquid in PBS, 0.05% sodium azide.

P Type

Mab

Purity

Purified by ion exchange chromatography.

Isotype

IgM,k

References

1. Albert, P.R., et al., J. Biol. Chem. 265(10): 5825-5832 (1990). 2. Cardenas, C.G., et al., J. Neurophys. 77(6): 3284-3296 (1997).

Additional Info

Recognizes rat Seratonin receptor 1A. Species Crossreactivity: human.

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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