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SERPINA1 pAb

SERPINA1 pAb

Cat no: BS5593


Supplier: Bioworld Technology, Inc.
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SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. Antral SERPINA1 expression is particularly induced by H. pylori infection. lung and prostate cancers have shown a significant increase in SERPINA1 serum levels compared with healthy controls though breast cancers did not show a significant change. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance between elastase produced by leukocytes during phagocytosis.
Catalogue number: BS5593
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P01009
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 320-365 of Human SERPINA1.
Species: SERPINA1 pAb detects endogenous levels of SERPINA1 protein.
Molecular weight: ~ 46, 55 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; Short peptide from AAT; SPAAT; AAT; PI; ORF Names: PRO0684, PRO2209; (alpha)-1-antitrypsin; (alpha)-1 protease inhibitor; (alpha)-1-antiproteinase; (alpha)1-antitrypsin; (alpha)1 protease inhibitor; (alpha)1-antiproteinase; (alpha)1 antitrypsin; (alpha)1 antiproteinase
Additional info: For research use only, not for use in diagnostic procedure.

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