SERPING1 pAb

The serine proteinase inhibitors (serpins) comprise a superfamily of proteins with a diverse set of functions, including the control of complement activation, blood coagulation, programmed cell death and cell development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The most abundant serpins in human plasma are a-1-antitrypsin (AAT) and a-1-antichymotrypsin (AACT). Other serpin family members include pigment epithelium-derived growth factor (PEDF), human protease nexin 1 (PN-1), protease inhibitor 6 (PI-6), thyroxine-binding globulin precursor (TBG), protease inhibitor 9 (PI-9), serine protease inhibitor 3 (Spi3), plasma protease C1 inhibitor (C1INH), Headpin, SerpinB12, monocyte/neutrophil elastase inhibitor members 1a,1b and 1c (M/NEI) and squamous cell carcinoma antigens 1 and 2 (SCCA1/2). Antithrombin-III (ATIII) is a crucial serine protease inhibitor that regulates the coagulation cascade in blood and inhibits Thrombin.

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SPECIFICATIONS

Catalog Number

BS6540

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human SERPING1.

Species

SERPING1 pAb detects endogenous levels of SERPING1 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P05155

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 55 kDa

Alternative Names

C1 esterase inhibitor; C1 INH; C1 inhibitor; C1-inhibiting factor; C1IN; C1Inh; C1NH; esterase inhibitor; HAE1; IC1; Plasma protease C1 inhibitor; Serine (or cysteine) proteinase inhibitor clade G member 1; Serpin G1; SERPING1;