SFRS7, NT (SRSF7, SFRS7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7)

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

041634

Size

200ul

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Kimura, T., et al. Med Mol Morphol 43(3):145-157(2010)\nEscudero-Paunetto, L., et al. Virology 401(2):155-164(2010)\nManley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)\nValente, S.T., et al. Mol. Cell 36(2):279-289(2009)\nShepard, P.J., et al. Genome Biol. 10 (10), 242 (2009) :

Additional Info

Human

Alternative Names

SRSF7, SFRS7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7