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SFRS8 pAb

SFRS8 pAb

Cat no: BS5952


Supplier: Bioworld Technology, Inc.
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SWAP (suppressor of white apricot protein homolog), also known as SFRS8 (splicing factor, arginine/serine-rich 8), is the 951 amino acid human homolog of a Drosophilia splicing protein. Localized to the nucleus, SWAP contains two SURP repeats through which it is thought to mediate splicing events, possibly regulating the alternative splicing of Fibronectin and CD45RC. SWAP regulates its own expression levels (via control of splicing in its first two introns) and may act in tandem with other arginine/serine-rich splicing factors to control protein expression. The gene encoding SWAP is located on a region of chromosome 12 that is related to asthma susceptibility, possibly indicating a role for SWAP in the development of asthma. Multiple isoforms of SWAP exist due to alternative splicing events.
Catalogue number: BS5952
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q12872
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 251-296 of Human SFRS8.
Species: SFRS8 pAb detects endogenous levels of SFRS8 protein.
Molecular weight: ~ 105 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Splicing factor, suppressor of white-apricot homolog; Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog; SFSWAP; SFRS8; SWAP
Additional info: For research use only, not for use in diagnostic procedure.

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