SFT2D2 pAb

SFT2D2 (SFT2 domain-containing protein 2) is a 160 amino acid multi-pass membrane protein that belongs to the SFT2 family. SFT2D2 may be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. The SFT2D2 gene is conserved in dog, cow, mouse, rat, chicken, A.thaliana and rice, and maps to human chromosome 1q24.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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SPECIFICATIONS

Catalog Number

BS5928

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 110-155 of Human SFT2D2.

Species

SFT2D2 pAb detects endogenous levels of SFT2D2 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

O95562

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul