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SIP1 (E101) Peptide

SIP1 (E101) Peptide

Cat no: BS3009P

Supplier: Bioworld Technology, Inc.
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SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins. SIP1, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SIP1 contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1, also known as SMADIP1 and ZFHX1B, can be induced by TGFbeta treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart disease
Catalogue number: BS3009P
Applications: Block/Neutralize/Inhibit
Swiss prot: O60315
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide SIP1 (E101). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: ZFHX1B; KIAA0569; SIP-1; SIP1; SMADIP1; ZEB2; ZFX1B
Additional info: This peptide can be used with studies using BS3009 SIP1 (E101) pAb.

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