Home  >  Products  >  SIRT1 (Sirtuin 1, Sirtuin-1, Sirtuin Type 1, hSIRT1, NAD-dependent Deacetylase Sirtuin-1, hSIR2, SIR2-like Protein 1, SIR2L1)
SIRT1 (Sirtuin 1, Sirtuin-1, Sirtuin Type 1, hSIRT1, NAD-dependent Deacetylase Sirtuin-1, hSIR2, SIR2-like Protein 1, SIR2L1)

SIRT1 (Sirtuin 1, Sirtuin-1, Sirtuin Type 1, hSIRT1, NAD-dependent Deacetylase Sirtuin-1, hSIR2, SIR2-like Protein 1, SIR2L1)

Cat no: S1013-88A10

Supplier: United States Biological
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.05-0.2ug/ml, observed in lysates of cell line Jurkat on ~120kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1013-88A10
Reactivities: Human, Mouse
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human SIRT1. Species sequence homology: Mouse.

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