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SIRT6 (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like Protein 6, SIR2L6)

SIRT6 (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like Protein 6, SIR2L6)

Cat no: S1013-88K3

Supplier: United States Biological
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Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Cellular Localization: Nuclear Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S1013-88K3
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Tris-citrate/phosphate (pH 7-8)
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Michishita, E., et al. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Bio. Cell. 16: 4623-4635 (2005)
Additional info: Species Crossreactivity: Human. Other species have not been tested. The immunogen used for the production of this antibody shows 72% homology with the rat protein.

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