Skp1 p19 (P72) Peptide

Cat no: BS1694P

Supplier: Bioworld Technology, Inc.

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Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DP-1 and E2F and retinoblastoma protein p110. Two cyclin A-Cdk2 complex binding proteins, Skp1 p19 and Skp2 p45, have been described. Although the Skps (S phase kinase-associated proteins) associate with the active cyclin A-Cdk2 complex, they do not exhibit any regulatory effects on the complex. Abolition of Skp2 p45 function by either microinjection of anti-p45 antibodies or addition of antisense oligonucleotides prevents entry into S phase of both normal and transformed cells.

Catalogue number:	BS1694P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P63208
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Skp1 p19 (P72). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	p19A; RNA polymerase II elongation factor-like protein; Organ of Corti protein 2; OCP-2; OCP-II; Transcription elongation factor B; SIII; SKP1; EMC19; OCP2; SKP1A; TCEB1L
Additional info:	This peptide can be used with studies using BS1694 Skp1 p19 (P72) pAb.

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Skp1 p19 (P72) Peptide

Cat no: BS1694P

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