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SLC25A14 (Brain Mitochondrial Carrier Protein 1, BMCP-1, Mitochondrial Uncoupling Protein 5, UCP 5, Solute Carrier Family 25 Member 14, BMCP1, UCP5, UNQ791/PRO1682, MGC149543)

Cat no: 138357

SLC25A14 (Brain Mitochondrial Carrier Protein 1, BMCP-1, Mitochondrial Uncoupling Protein 5, UCP 5, Solute Carrier Family 25 Member 14, BMCP1, UCP5, UNQ791/PRO1682, MGC149543)

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. SLC25A14 has an N-terminal hydrophobic domain that is not present in other UCPs.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 2.5ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138357

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Can

Form

Supplied as a lyophilized powder in PBS. Reconstitute with 100ul dH2O to 1mg/ml.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Additional Info

Recognizes SLC25A14. Species Crossreactivity: Human, mouse, rat and canine.

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