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Smad4 (L43) Peptide

Smad4 (L43) Peptide

Cat no: BS2050P

Supplier: Bioworld Technology, Inc.
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Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFbeta and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members.
Catalogue number: BS2050P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13485
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Smad4 (L43). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: SMAD 4; hSMAD4; Deletion target in pancreatic carcinoma 4; SMAD4; DPC4; MADH4
Additional info: This peptide can be used with studies using BS2050 Smad4 (L43) pAb.

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