SMARCA4 (R1614) pAb

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2(alpha)) and Brg-1 (also designated SNF2(beta)) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles.

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SPECIFICATIONS

Catalog Number

BS2950

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 1600-1650 of Human SMARCA4.

Species

SMARCA4 (R1614) pAb detects endogenous levels of SMARCA4 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

P51532

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 200, 200 kDa

Alternative Names

ATP-dependent helicase SMARCA4\nBRG1-associated factor 190A\nShort name=BAF190A\nMitotic growth and transcription activator\nProtein BRG-1\nProtein brahma homolog 1\nSNF2-beta\nSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4