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SNAP 25 (E183) Peptide

Cat no: BS1327P

SNAP 25 (E183) Peptide

Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including alpha- and gamma -SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding.

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SPECIFICATIONS

Catalog Number

BS1327P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide SNAP 25 (E183). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P60880

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1327 SNAP 25 (E183) pAb.

Alternative Names

SNAP25; BA416N4.2; DJ1068F16.2; FLJ23079; RIC-4; RIC4; SNAP; SNAP-25; SUP

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