SOD1 pAb

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, Zn SOD (EC SOD/SOD3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain.

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SPECIFICATIONS

Catalog Number

BS6057

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human SOD1.

Species

SOD1 pAb detects endogenous levels of SOD1 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P00441

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 18 kDa

Alternative Names

ALS 1; \nALS; \nALS1; \nAmyotrophic lateral sclerosis 1 adult; \nAmyotrophic lateral sclerosis 1; \nCu/Zn SOD; \nCu/Zn superoxide dismutase; \nHomodimer; \nhSod1; \nIndophenoloxidase A; \nIPOA; \nMn superoxide dismutase; \nSOD 1; \nSOD; \nSOD soluble; \nSOD1; \nSOD2; \nSODC; \nSODC; \nSoluble indophenoloxidase A; \nSuperoxide dismutase [Cu-Zn]; \nSuperoxide dismutase 1; \nSuperoxide dismutase 1 soluble; \nSuperoxide dismutase Cu Zn; \nSuperoxide dismutase cystolic; \n