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SORD pAb

SORD pAb

Cat no: BS6735


Supplier: Bioworld Technology, Inc.
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Sorbitol Dehydrogenase, also known as L-iditol 2-dehydrogenase, SORD or SORD1, is a 357 amino acid member of the zinc-containing alcohol dehydrogenase family. Widely expressed with highest expression in kidney and in the lens of the eye, Sorbitol Dehydrogenase enzymatically catalyzes the zinc-dependent interconversion of polyols, such as such as sorbitol and xylitol, to their respective ketoses. These reactions require NAD+ as an oxidizing agent and, together with Aldose Reductase, they comprise the sorbitol pathway that is involved in sugar production. Sorbitol Dehydrogenase deficiency leads to defects in this pathway and a subsequent accumulation of sorbitol within the cell, a condition that may be associated with diabetic complications such as cataracts and microvascular problems.
Catalogue number: BS6735
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q00796
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human SORD.
Species: SORD pAb detects endogenous levels of SORD protein.
Molecular weight: ~ 38 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: SORD 1; SORD; SORD1; Sorbitol dehydrogenase
Additional info: For research use only, not for use in diagnostic procedure.

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