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SR-1A (F321) pAb

SR-1A (F321) pAb

Cat no: BS2180

Supplier: Bioworld Technology, Inc.
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The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. (beta)-adrenergic bound to adrenaline activates adenylyl cyclase, while (alpha)2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the (alpha)2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A,-1B, -1D, -1E and -1F.
Catalogue number: BS2180
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P08908
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 291-340 of Human SR-1A.
Species: SR-1A (F321) pAb detects endogenous levels of SR-1A protein.
Molecular weight: ~ 46 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: 5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; HTR1A; ADRB2RL1, ADRBRL1
Additional info: For research use only, not for use in diagnostic procedure.

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