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SRY (L80) Peptide

Cat no: BS2037P

SRY (L80) Peptide

SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.

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SPECIFICATIONS

Catalog Number

BS2037P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide SRY (L80). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q05066

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2037 SRY (L80) pAb.

Alternative Names

SRY (Sex determining region Y)-box 13. isoform CRA_b; SOX13; RP11-74C13.1. ICA12. MGC117216. SRY-box 13. Sox-13

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