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STAM2 (T188) Peptide

Cat no: BS1807P

STAM2 (T188) Peptide

STAM contains an SH3 (Src homology 3) motif as well as an immunoreceptor tyrosine-based activation (ITAM) motif, both of which appear to be required for c-Myc induction in response to IL-2 and GM-CSF. STAM associates with JAK3 and JAK2 via its ITAM region, and it is tyrosine phosphorylated by JAK3 and JAK2 after stimulation with IL-2 and GM-CSF, respectively. STAM2, also known as Hbp, is a protein that is highly related to STAM. Similar to STAM, STAM2 functions downstream of JAK kinases and can be phosphorylated in response to cytokines. Due to alternative splicing events, two isoforms of STAM2 exist, namely STAM2A and STAM2B.

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SPECIFICATIONS

Catalog Number

BS1807P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide STAM2 (T188). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

O75886

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1807 STAM2 (T188) pAb.

Alternative Names

Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein; STAM2; HBP

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