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STAP2 pAb

STAP2 pAb

Cat no: BS60284


Supplier: Bioworld Technology, Inc.
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STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK. BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines. Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain. STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis.
Catalogue number: BS60284
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q9UGK3
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: A synthetic peptide corresponding to residues in Human STAP2.
Species: STAP2 pAb detects endogenous levels of STAP2 protein.
Molecular weight: ~ 48 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Signal-transducing adaptor protein 2; STAP-2; Breast tumor kinase substrate; BRK substrate; BKS
Additional info: For research use only, not for use in diagnostic procedure.

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