STMN2 pAb

SCG10, also designated stathmin-like 2 (STMN2), is a neuronal growth-associated protein (nGAP) that belongs to the stathmin family. Stathmin family phosphoproteins are involved in regulation of microtubule dynamics and signal transduction. SCG10, which is membrane- associated and neuron-specific, may participate in neuronal differentiation and may modulate membrane interaction with the cytoskeleton during neurite outgrowth. The SCG10 protein binds to and inhibits the assembly of microtubules, and can also induce microtubule disassembly. The assembly and disassembly of microtubules is necessary for cell division, intracellular transport and cell movements, as well as neurite elongation, outgrowth and branching in the developing nervous system.

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SPECIFICATIONS

Catalog Number

BS5948

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 134-179 of Human STMN2.

Species

STMN2 pAb detects endogenous levels of STMN2 protein.

Dilutions

WB: 1:500~1:1000\r

Swiss Prot

Q93045

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul