Home  >  Products  >  STXBP1 (Syntaxin-binding Protein 1, MUNC18-1, N-Sec1, Protein Unc-18 Homolog 1, Unc18-1, Protein Unc-18 Homolog A, Unc-18A, p67, UNC18A)
STXBP1 (Syntaxin-binding Protein 1, MUNC18-1, N-Sec1, Protein Unc-18 Homolog 1, Unc18-1, Protein Unc-18 Homolog A, Unc-18A, p67, UNC18A)

STXBP1 (Syntaxin-binding Protein 1, MUNC18-1, N-Sec1, Protein Unc-18 Homolog 1, Unc18-1, Protein Unc-18 Homolog A, Unc-18A, p67, UNC18A)

Cat no: S9205-80A

Supplier: United States Biological
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May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 0.1-0.3ug/ml, observed in human and mouse brain lysates on ~75kD bands Immunohistochemistry (Paraffin): 5-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S9205-80A
Reactivities: Human, Mouse
Hosts: Goat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Swanson DA, Steel JM, Valle D. Identification and characterization of the human ortholog of rat STXBP1, a protein implicated in vesicle trafficking and neurotransmitter release. Genomics. 1998 Mar 15;48(3):373-6.
Additional info: Recognizes STXBP1. Species Crossreactivity: Human and mouse.

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