Synaptophysin (L128) Peptide

Cat no: BS1345P

Supplier: Bioworld Technology, Inc.

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Synaptic vesicles participate in a cycle of fusion with the plasma membrane and reformation by endocytosis. Synaptic vesicle protein synaptophysin (SYP) is targeted to early endosomes in transfected fibroblasts and in neuroendocrine cells. SYP is an N-glycosylated intergral membrane protein found in neurons and endocrine cells that associates into hexamers to form a large conductance channel. SYP contains four transmembrane domains and may function as a gap juction-like channel. Membrane cholesterol specfically interacts with SYP to play a role in vesicle formation. Synaptobrevin (VAMP) also binds to SYP and the resultant complex is upregulated during neuronal development, but is absent in exocytosis fusion complex. Thus, the synaptophysin-synaptobrevin complex is not essential for exocytosis, but rather provides a pool of synaptobrevin for exocytosis.

Catalogue number:	BS1345P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P08247
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Synaptophysin (L128). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Synaptophysin; Major synaptic vesicle protein p38; SYP
Additional info:	This peptide can be used with studies using BS1345 Synaptophysin (L128) pAb.

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Synaptophysin (L128) Peptide

Cat no: BS1345P

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