Synuclein, alpha

Supplier:

United States Biological

Cat no: S9500-12

Synuclein, alpha

Recommended Secondary Reagents: Donkey anti-Sheep\\Goat IgG: HRP\n\nRecommended Positive Control Tissue: Brain, Spinal Cord.\n\nApplications:\nImmunohistochemistry: Paraffin. 1:300\nELISA: 1:1000 vs immunizing peptide\nOptimal working dilutions to be determined by researcher.\n\nImmunohistochemistry: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

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SPECIFICATIONS

Catalog Number

S9500-12

Size

100ul

Applications

ELISA, IHC

Hosts

Goat

Reactivities

Hum

Form

Serum. Supplied as a liquid with 0.1% sodium azide.

P Type

Pab

Purity

Serum.

Isotype

IgG

References

1. Spillantini, M.G. et al. (1997). a-synuclein in Lewy bodies. Nature 388: 839-840.2. Gai, W.P. et al. (1997). Multiple-system atrophy: a new alpha-synuclein disease. Lancet 352: 547-548.

Additional Info

Recognizes human alpha-synuclein. The alpha-synuclein gene, located on chromosome 4, has been linked to early onset autosomal dominant Parkinson's disease. The protein is abundant in the nervous system and is known to be the precursor of the non-beta amyloid component protein (NACP) of Alzheimer's disease. Alpha-synuclein has also been found to be associated with other neurodegenerative diseases such as multiple system atrophy and dementia with Lewy's bodies.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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