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T-type Ca++ CP (alpha)1H (P492) pAb

T-type Ca++ CP (alpha)1H (P492) pAb

Cat no: BS3413

Supplier: Bioworld Technology, Inc.
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Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an (alpha)1 subunit, an intracellular (beta) subunit, a disulfide linked (alpha)2/(delta) subunit and a transmembrane (gamma) subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
Catalogue number: BS3413
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O95180
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 461-510 of Human T-type Ca++ CP (alpha)1H.
Species: T-type Ca++ CP (alpha)1H (P492) pAb detects endogenous levels of T-type Ca++ CP (alpha)1H protein.
Molecular weight: ~ 259 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CACNA1H, Voltage-dependent T-type calcium channel subunit alpha-1H, Low-voltage-activated calcium channel alpha1 3.2 subunit, CACNA1H
Additional info: For research use only, not for use in diagnostic procedure.

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