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TACC3 (T813) Peptide

TACC3 (T813) Peptide

Cat no: BS2580P


Supplier: Bioworld Technology, Inc.
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TACC1 (transforming acidic coiled coil gene 1) is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Catalogue number: BS2580P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9Y6A5
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TACC3 (T813). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: TACC3; ERIC-1; ERIC1; MGC117382; MGC133242; TACC1
Additional info: This peptide can be used with studies using BS2580 TACC3 (T813) pAb.

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