TAF II p135/p105 (E977) pAb

Cat no: BS2239

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

Catalogue number:	BS2239
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	O00268/Q92750
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 951-1000 of Human TAF II p135.
Species:	TAF II p135/p105 (E977) pAb detects endogenous levels of TAF II p135/p105 protein.
Molecular weight:	~ 135 kDa,~ 105 kDa,
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	TAF(II)135; TAF2C; TAF2C1; TAF4A; TAFII 130; TAFII 135; TAFII130; TAFII135; TBP associated factor 4; TBP Associated transcription Factor family member; Transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4;
Additional info:	For research use only, not for use in diagnostic procedure.

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TAF II p135/p105 (E977) pAb

Cat no: BS2239

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