TBLR1 mAb

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, th ereby allowing cofactor exchange, and transcription activation.

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SPECIFICATIONS

Catalog Number

MB0051

Size

100ug/100ul

Applications

IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse

Form

liquid

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human TBLR1.

Species

This antibody detects endogenous levels of TBLR1 and does not cross-react with related proteins

Dilutions

WB: 1:1000\nICC: 1:50~200\nIHC: 1:50~500

Swiss Prot

Q9BZK7

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

Predicted band size:60KDa \nObserved band size:60Kda

Alternative Names

F-box-like/WD repeat-containing protein TBL1XR1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1; TBL1XR1; IRA1; TBLR1