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TCP-1E Peptide

Cat no: BS5958P

TCP-1E Peptide

The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma , delta, E, ?, ? and 0, each encoded by a different gene. Two ? subunits have been described: TCP-1 ? (also designated TCP-1 ?1) and TCP-1 ?2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

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SPECIFICATIONS

Catalog Number

BS5958P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide TCP-1E. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P48643

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5958 TCP-1E pAb.

Alternative Names

T-complex protein 1 subunit epsilon; TCP-1-epsilon; TCP1E; TCP 1E; TCP1-E; CCT-epsilon; CCT-E; CCTE; CCT5; CCTE; KIAA0098

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