TFE3 Peptide

Cat no: BS5962P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination. TFEB binds to the major late promoter of adenovirus and specifically associates with DNA as both a homodimer and a heterodimer with TFE3. TFEB is expressed at low levels in the embryo but at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization of the placenta.

Catalogue number:	BS5962P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P19532
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide TFE3. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33; TFE-3; BHLHE33
Additional info:	This peptide can be used with studies using BS5962 TFE3 pAb.

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TFE3 Peptide

Cat no: BS5962P

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