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TFIIA-alpha (E311) Peptide

TFIIA-alpha (E311) Peptide

Cat no: BS2282P

Supplier: Bioworld Technology, Inc.
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Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. Recognition of the TATA binding element by TBP, one of the first steps in transcription initiation, may be regulated by TFIIA. TFIIA consists of three subunits designated TFIIA-alpha, TFIIA-beta and TFIIA-gamma , and it interacts with both TBP and a TAF (TBP-associated factor). It has been demonstrated that the basic region of TBP is essential for TFIIA-dependent function of TBP.
Catalogue number: BS2282P
Applications: Block/Neutralize/Inhibit
Swiss prot: P52655
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide TFIIA-alpha (E311). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: General transcription factor II A. 1-like factor; ALF; MGC26254
Additional info: This peptide can be used with studies using BS2282 TFIIA-alpha (E311) pAb.

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