TGF(alpha) pAb

Cat no: BS6452

Supplier: Bioworld Technology, Inc.

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Additional Information

Transforming growth factor-(alpha) (TGF(alpha)) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGF(alpha) is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGF(alpha) binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-(beta). TGFa is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGF(alpha) bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy

Catalogue number:	BS6452
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P01135
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human TGF(alpha).
Species:	TGF-alpha pAb detects endogenous levels of TGF-alpha protein.
Molecular weight:	~ 10, 17 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	EGF like TGF; EGF-like TGF; ETGF; TFGA; TGF A; TGF type 1; TGF-alpha; TGFA; TGFA; Transforming growth factor alpha; Transforming growth factor alpha precursor; Wa1; Waved 1;
Additional info:	For research use only, not for use in diagnostic procedure.

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TGF(alpha) pAb

Cat no: BS6452

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