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TGF(alpha) (R139) pAb

TGF(alpha) (R139) pAb

Cat no: BS1359

Supplier: Bioworld Technology, Inc.
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Transforming growth factor (alpha) (TGF(alpha)) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGF(alpha) is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGF(alpha) binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor (beta). TGF(alpha) is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGF(alpha) bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.
Catalogue number: BS1359
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P01135
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 111-160 of Human TGF(alpha).
Species: TGF (alpha) (R139) pAb detects endogenous levels of TGF (alpha) protein.
Molecular weight: ~ 10, 17 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Protransforming growth factor alpha; Transforming growth factor alpha; TGF-alpha; EGF-like TGF; ETGF; TGF type 1; TGFA; TGF (alpha)
Additional info: For research use only, not for use in diagnostic procedure.

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